11 studies
Research Library
Curated findings from peer-reviewed longevity and health science journals, graded by evidence strength.
Eight Hyped Compounds Failed to Extend Lifespan in a Major Mouse Study
The NIA's Interventions Testing Program tested eight compounds across three lab sites in genetically diverse mice. None extended lifespan. That includes astaxanthin, alpha-ketoglutarate, pioglitazone,...
This study suggests that dose and timing matter enormously, and early lifespan results in mice often don't hold up.
Fish That Age Fast Reveal Predictable 'Life Stages' in Aging
Scientists tracked African killifish behavior continuously from adolescence to death. Long-lived fish behaved differently from short-lived ones surprisingly early in life. Machine learning could actua...
This study suggests aging may follow structured, predictable stages rather than a gradual slide.
Vitamin C May Slow Primate Aging by Blocking Iron-Driven Cell Damage
As primates age, iron builds up in tissues and fuels a chain reaction of fat damage in cells. Researchers call this process "ferro-aging" and found that a specific enzyme (ACSL4) drives it. When aged ...
This study suggests vitamin C may help counter age-related iron-driven cell damage in primates.
A Newly Found Enzyme Breaks Down NAD+ Inside Mitochondria
Scientists identified a mitochondrial enzyme called SelO that breaks NAD+ into NMN and AMP. This reaction ramps up when mitochondria are working hard, essentially acting as a brake to prevent metaboli...
This study suggests mitochondrial NAD+ regulation is more complex than previously understood.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Your Weekly Edge
Receive the latest longevity insights, exclusive event invites, and science-backed tips to help you live longer and thrive.
