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Journal ArticleNature communications·May 2026

Senolytics Plus TB Drugs Boost Survival in Infected Mice

Key Insight

This study suggests senolytic drugs may warrant testing as add-on therapy for tuberculosis in humans.


Tuberculosis triggers some lung cells to become senescent (zombie-like cells that won't die but cause damage). Researchers gave infected mice a senolytic cocktail of dasatinib, quercetin, and fisetin alongside standard TB treatment. The combo improved survival and reduced lung damage, especially in older mice.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.