Caloric Restriction Slows Aging Most in the Heart and Metabolism
Graded Strong — randomized controlled trial in 185 healthy adults over 2 years, with effects holding at both 12 and 24 months, though outcomes are biomarker-based organ ages in a subset of the full trial.
- Design
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- Participants
- 185
- Duration
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- Funding
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This study suggests caloric restriction may preferentially protect cardiovascular and metabolic health.
Cutting calories doesn't slow aging evenly across all organs. In a two-year trial, 185 adults were randomly assigned to caloric restriction or normal eating. The caloric restriction group aged about one year less in their cardiovascular and metabolic systems over 24 months. Kidney aging, however, didn't budge, and liver aging only slowed modestly at the two-year mark.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
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