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Journal ArticleFrontiers in molecular neuroscience·Graded and published ·Last edited

Saffron Eased Memory Loss and Anxiety in Stressed Older Rats

Graded Preliminary — four-week study in aged rats under daily cold stress, with no human data and the number of animals not reported.

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The authors report no commercial or financial conflicts.
Key Insight

This early animal study suggests saffron extract may support memory under chronic stress.


Aged rats put through daily cold stress for four weeks became more anxious and did worse on memory tests. Rats that got saffron extract by mouth showed less anxious behavior and better performance on two different memory tasks. The extract was loaded with crocin and other plant compounds that mop up damaging molecules. This is animal work only, so it doesn't tell us what saffron does for stressed humans.

Conflict of Interest Disclosure: The authors report no commercial or financial conflicts.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.