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Journal ArticleTranslational psychiatry·Graded and published ·Last edited

Longer Bursts of Brisk Activity Linked to Less Dementia

Graded Moderate — a large observational study of 66,483 people over about seven and a half years; it shows links but cannot prove that the activity itself protects.

Design
Prospective cohort study
Participants
66,483
Duration
7.5 years
Funding
City University of Hong Kong; Guangdong and Hong Kong Universities 1+1+1 Joint…
Key Insight

People who moved hard for longer stretches at a time were later diagnosed with dementia, depression or anxiety less often.


Does a single longer stretch of activity count for more than many short ones scattered through the day? Until now, nobody knew. Data from the UK point toward the longer stretch. People whose activity came in longer bouts of moderate to vigorous effort were later diagnosed with dementia less often. The lowest risk came with bouts of 13 minutes: 72 percent lower than in people who never moved that hard.

The 66,483 adults wore a wrist activity tracker for one week. They take part in the UK Biobank, a large British health study. Researchers then followed them for about seven and a half years on average. Longer bouts also went along with less depression and anxiety. Here the lowest risk appeared at 36 minutes in one go, roughly half the risk. This held even after accounting for how much people moved in total.

Brain scans from part of the group fit the picture. Longer bouts went with a larger left hippocampus, a brain region whose shrinking is a known sign of Alzheimer's. The study only observed people, so it cannot show that the activity itself protects. Only 425 people developed dementia, and most participants were white.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.