Coenzyme Q10

Coenzyme Q10 (ubiquinone) is a lipid-soluble molecule essential for mitochondrial electron transport and ATP production, and an intracellular antioxidant. Endogenous levels decline with age and with statin use. Clinical evidence is strongest in heart failure, where supplementation is associated with reduced mortality and improved symptoms in some trials. Effects on blood pressure and statin-related muscle symptoms are modest; longevity benefits in healthy adults are not established.