# Vitamin D Eased Fatty Liver and Blood Sugar Problems in Obese Rats

*Vitamin D attenuates Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and downregulates hepatic gluconeogenesis in obesity.*

- **Evidence Level**: Preliminary
- **Publication Types**: Journal Article
- **Journal**: The Journal of nutritional biochemistry
- **Sample Size**: Wistar rats on cafeteria or standard diet (number not specified)
- **Authors**: Cordeiro MM, Lucredi NC, Pateis VO, Souza GH, Duarte ALR, Scomparin DX, Natali MRM, Sá-Nakanishi AB, Bracht L, Bracht A, Comar JF
- **Published**: 2026-06-20
- **Topics**: vitamin D, fatty liver, blood sugar
- **DOI**: https://doi.org/10.1016/j.jnutbio.2026.110450
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/42323099/

## Summary

Junk food fed rats developed fatty liver, insulin resistance, and inflammation, much like people on a poor diet. Weekly vitamin D cut their food intake and weight gain, and improved blood sugar control and liver fat. It also calmed inflammation markers in the liver. This was rats, so it does not prove the same effect in people.

## Practical Takeaway

This animal study suggests vitamin D may be linked to better liver and blood sugar health in obesity.

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