# NAD+ and muscle

6 papers in the library, strongest Moderate.

**Graded Moderate**: Cross-sectional multiomics study of muscle in young and older adults with differing fitness, though training was not assigned and outcomes are molecular markers rather than health.

## Papers (6)

- [Regular Exercise May Rewind the Molecular Clock in Aging Muscle](https://longevity-china.com/en/research/regular-exercise-may-rewind-the-molecular-clock-in-aging-muscle) · Moderate · 2026 · Nature aging
- [NR May Slow Muscle Aging Clocks While Hard Interval Training Speeds Some Up](https://longevity-china.com/en/research/nr-may-slow-muscle-aging-clocks-while-hard-interval-training-speeds-some-up) · Preliminary · 2026 · Aging cell
- [Nicotinamide Riboside May Shield Female Mouse Muscle From Heat Damage](https://longevity-china.com/en/research/nicotinamide-riboside-may-shield-female-mouse-muscle-from-heat-damage) · Preliminary · n = 6 · 2026 · Muscles (Basel, Switzerland)
- [Nicotinamide Riboside Protected Mitochondria in Mice With a Rare Muscle Disease](https://longevity-china.com/en/research/nicotinamide-riboside-protected-mitochondria-in-mice-with-a-rare-muscle-disease) · Preliminary · n = 6 · 2026 · Human molecular genetics
- [Why NAD+ Boosters Like NR May Be a Double-Edged Sword for Muscle](https://longevity-china.com/en/research/why-nad-boosters-like-nr-may-be-a-double-edged-sword-for-muscle) · Preliminary · 2026 · Frontiers in nutrition
- [NMN Plus Apigenin May Protect Aging Muscle and Bone Better Together](https://longevity-china.com/en/research/nmn-plus-apigenin-may-protect-aging-muscle-and-bone-better-together) · Preliminary · 2026 · Aging cell

## How this map is computed

A mark's size is the number of papers we hold on that pairing. It is a count, not a weighting by study design or sample size.

The fill shows the strongest grade in the cell. One Strong paper among four Preliminary ones still fills it dark, so open the cell to see the rest.

Grades and verdicts are assigned by a named person, never by counting.

An empty cell is a finding: nobody in our library has run that trial yet.

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_Canonical: https://longevity-china.com/en/evidence/nad-precursors/muscle · Part of Longevity Cities_